Primary Cancerous Bone Tumors

Bone tumors are abnormal cell growth that may or may not stop after a certain point in the absence of surgical intervention. Bone tumors may be cancerous or non-cancerous, may or may not present with symptoms, and may or may not affect the health of the patient, depending on the type. The three types of bone tumors that may cause back pain, bone pain, and other related musculoskeletal pain include noncancerous bone tumors, primary cancerous bone tumors, and metastatic bone tumors. The types of tumors are differentiated by their capacity for malignancy, the type of bones and location along the bones they develop, and their cause. Noncancerous bone tumors typically affect younger individuals 30 and younger, can usually be removed surgically, and typically have a good patient prognosis because they are less likely to spread to the bloodstream and other organs. Primary cancerous bone tumors refer to the original site of cancerous bone tumors that have spread or are likely to spread to other bones and organs in the absence of medical intervention. Examples of primary cancerous bone tumors include multiple myeloma, osteosarcoma, fibrosarcoma, chondrosarcoma, Ewing's tumor, and malignant lymphoma.

Multiple myeloma. Multiple myeloma, originated in the bone marrow of bones, and is the most common type of primary cancerous bone tumor. The bone marrow is where our red and white blood cells are produced. Older men and women are more commonly affected, and the site of the tumor(s) may be present in one or more locations of the body where the bone marrow is produced (the ends of the long bones in adults.) bone pain near the site of the tumor is the most common symptoms is the condition. Treatment is complex and often includes multiple medical interventions, including surgery, radiation therapy, and drugs.

Osteosarcoma. Osteosarcoma is the second most common type of primary cancerous tumor. Osteosarcomas may affect individuals of any age group, though most frequently in people between 10-20. Older patients with a previous diagnosis of Paget's disease are at an increased risk of developing osteosarcomas. These tumors may originate in nearly any bone, but are more common in the long bones proximal to the knee. If the progression isn't stopped, these tumors most often spread to the lungs. Swelling and pain are common early physical symptoms experienced by the patient. Though medical imaging procedures may provide doctors with some degree of certainty towards a correct diagnosis, the conformation of this type of primary cancerous bone tumor is usually confirmed with a biopsy. Previously, the treatment for these tumor(s) required amputation of the entire bone to be amputated, but modern technology and techniques often allows doctors the ability to remove the tumors while saving the bone. Osteosarcomas are usually treated with a combination of surgery and chemotherapy. Typically, the patient is given one or more rounds of chemo first before the entire tumor is removed. The prognosis for successful treatment is survival for at least 5 years after diagnosis for about 75 of treated patients.

Next, read on about the diagnosis and treatment phase of malignant fibrous histiocytomas, fibrosarcomas, Ewing's tumor, and malignant lymphoma of bone.